Can you get gray hair in your 20s?

 GOING GRAY EARLY (PREMATURE GRAY HAIR)| DR DRAY

#ANTIAGING #HAIR #SKINCARE #DRDRAY TODAY I TALK ABOUT GRAY HAIR AND GOING GRAY EARLY. THIS VIDEO IS NOT SPONSORED. 💜REFERENCES Tobin DJ, Paus R. Graying: Gerontobiology of the hair follicle pigmentary unit. Exp Gerontol. 2001;36:29–54 Panhard S, Lozano I, Loussouarn G. Greying of the human hair: A worldwide survey, revisiting the ‘50’ rule of thumb. Br J Dermatol. 2012;167:865–73. Ito S, Wakamatsu K. Diversity of human hair pigmentation as studied by chemical analysis of eumelanin and pheomelanin. J Eur Acad Dermatol Venereol. 2011;25:1369–80. Rees J. Plenty new under the sun. J Invest Dermatol. 2006;126:1691–2. Slominski A, Wortsman J, Plonka PM, Schallreuter KU, Paus R, Tobin DJ. Hair follicle pigmentation. J Invest Dermatol. 2005;124:13–21. Peters EM, Imfeld D, Gräub R. Graying of the human hair follicle. J Cosmet Sci. 2011;62:121–5. Arck PC, Overall R, Spatz K, Liezman C, Handjiski B, Klapp BF, et al. Towards a “free radical theory of graying”: Melanocyte apoptosis in the aging human hair follicle is an indicator of oxidative stress induced tissue damage. FASEB J. 2006;20:1567–9. Choi HI, Choi GI, Kim EK, Choi YJ, Sohn KC, Lee Y, et al. Hair greying is associated with active hair growth. Br J Dermatol. 2011;165:1183–9. Goodier M, Hordinsky M. Normal and aging hair biology and structure ‘aging and hair’ Curr Probl Dermatol. 2015;47:1–9. Daulatabad D, Singal A, Grover C, Chhillar N. Profile of Indian patients with premature canities. Indian J Dermatol Venereol Leprol. 2016;82:169–72. Trüeb RM. Oxidative stress in ageing of hair. Int J Trichology. 2009;1:6–14. Wood JM, Decker H, Hartmann H, Chavan B, Rokos H, Spencer JD, et al. Senile hair graying: H2O2-mediated oxidative stress affects human hair color by blunting methionine sulfoxide repair. FASEB J. 2009;23:2065–75. Irie M, Asami S, Nagata S, Miyata M, Kasai H. Relationships between perceived workload, stress and oxidative DNA damage. Int Arch Occup Environ Health. 2001;74:153–7. Akin Belli A, Etgu F, Ozbas Gok S, Kara B, Dogan G. Risk factors for premature hair graying in young Turkish adults. Pediatr Dermatol. 2016;33:438–42. Daulatabad D, Singal A, Grover C, Sharma SB, Chhillar N. Assessment of oxidative stress in patients with premature canities. Int J Trichology. 2015;7:91–4. Shi Y, Luo LF, Liu XM, Zhou Q, Xu SZ, Lei TC. Premature graying as a consequence of compromised antioxidant activity in hair bulb melanocytes and their precursors. PLoS One. 2014;9:e93589. Jimbow K, Chen H, Park JS, Thomas PD. Increased sensitivity of melanocytes to oxidative stress and abnormal expression of tyrosinase-related protein in vitiligo. Br J Dermatol. 2001;144:55–65 Dawber RP. Integumentary associations of pernicious anaemia. Br J Dermatol. 1970;82:221–3. van Beek N, Bodó E, Kromminga A, Gáspár E, Meyer K, Zmijewski MA, et al. Thyroid hormones directly alter human hair follicle functions: Anagen prolongation and stimulation of both hair matrix keratinocyte proliferation and hair pigmentation. J Clin Endocrinol Metab. 2008;93:4381–8. Hartmann JT, Kanz L. Sunitinib and periodic hair depigmentation due to temporary c-KIT inhibition. Arch Dermatol. 2008;144:1525–6. Sideras K, Menefee ME, Burton JK, Erlichman C, Bible KC, Ivy SP. Profound hair and skin hypopigmentation in an African American woman treated with the multi-targeted tyrosine kinase inhibitor pazopanib. J Clin Oncol. 2010;28:e312–3. Etienne G, Cony-Makhoul P, Mahon FX. Imatinib mesylate and gray hair. N Engl J Med. 2002;347:446. Jo SJ, Paik SH, Choi JW, Lee JH, Cho S, Kim KH, et al. Hair graying pattern depends on gender, onset age and smoking habits. Acta Derm Venereol. 2012;92:160–1. Mosley JG, Gibbs AC. Premature grey hair and hair loss among smokers: A new opportunity for health education? BMJ. 1996;313:1616. Zayed AA, Shahait AD, Ayoub MN, Yousef AM. Smokers' hair: Does smoking cause premature hair graying? Indian Dermatol Online J. 2013;4:90–2. Trüeb RM. Association between smoking and hair loss: Another opportunity for health education against smoking? Dermatology. 2003;206:189–91. 💜Subscribe! https://goo.gl/GS67rQ 💜Social media Instagram @drdrayzday Facebook @DrDrayzDay Twitter: @drdrayzday 📪Mail: PO Box 542234 Houston, TX 77254 Disclaimer: This video is not intended to provide diagnosis, treatment or medical advice. Content provided on this Youtube channel is for informational purposes only. Please consult with a physician or other healthcare professional regarding any medical or health related diagnosis or treatment options. Information on this Youtube channel should not be considered as a substitute for advice from a healthcare professional. The statements made about specific products throughout this video are not to diagnose, treat, cure or prevent disease.

• We asked a dermatologist to explain why hair turns gray, and why it can happen to some people as early as their 20s.
• According to Dr. Jennifer Chwalek, genetics will likely determine whether or not you will go gray, and how soon it will happen. 
• Our hair pigment is protected by an enzyme that fights the build-up of hydrogen peroxide.
• As we age, this enzyme declines, allowing the hydrogen peroxide to break down the melanin in the hair shaft, causing the color to change. 
• According to Chwalek, factors like stress and smoking that cause oxidative damage could also contribute to hair going gray.
• Visit Business Insider's homepage for more stories.

Following is a transcript of the video.

Graham Flanagan: Look at that silver fox. So distinguished, so sophisticated. Wow! But what if I told you that this guy was a millennial? It's true, just barely. According to Joe, he started going gray when he was 16. By 22, he was pretty much totally gray. Why does that happen? And why does hair turn gray in the first place? There's something about a silver fox, if you can pull it off.

Actor: When I got rid of my gray hair, I wanted a natural look. Graham: But many people hate the idea of going gray. There's an entire industry built around fighting it.

Actress: It's like you took off 10 years.

Actor: And in just five minutes.

Man: Just For Men. She'll love the way you look.

Flanagan: So why does it happen?

Dr. Jennifer Chwalek: The process of hair changing from darker color to white or gray with age is mainly due to genetics. It can be inherited from either parent. The color of our hair is determined by the form of hair pigment that we have. The pigment is actually produced along the hair shaft, and there are two main forms of hair pigment. There's eumelanin and pheomelanin. Eumelanin is what we see in brunettes and darker-haired people, and pheomelanin is what we see in blonds and redheads. The cells in our hair bulb produce a little bit of hydrogen peroxide, which is a metabolic byproduct, and typically there's an enzyme called catalase that breaks this down to water and oxygen. But as we age, there's declining levels of catalase, and this allows the build-up of hydrogen peroxide in the hair bulb, which damages and destroys the melanocytes, or the pigment-producing cells, of our hair.

Flanagan: So I wanted you to take a look at my colleague Joe here. Joe is technically a millennial. He started to go gray when he was 16, and by 22, it was pretty much gray all over. What happened to Joe?

Chwalek: So when individuals gray early in life before the age of 20, it's called premature graying, and this is due to genes. And we know there's one gene, in particular, that's been targeted called interferon regulatory factor 4, which is important in regulating and producing melanin in the hair. Joe was lucky enough to inherit some genes that predisposed him to developing gray hair early in life.

Flanagan: Obviously, Joe has gray hair on his head. When you go gray on your head, does the hair on the other parts of your body go gray as well? No, no, Joe, Joe! We can picture it.

Chwalek: So you can grow gray hair anywhere on your body. Wherever you have hair, the hair is susceptible to oxidative damage and eventually going gray.

Flanagan: So the main cause of going gray is genetics, but what role can stress play? After all, Obama didn't look like this when he showed up at the White House.

Chwalek: So it's controversial the role that stress has in hair graying. We know that stress creates oxidative damage in the body, and it's been linked to a lot of premature-aging syndromes. So it's thought that the stress, that stress causes oxidative damage, which may cause damage to the melanocytes and may cause us to grow gray earlier. We know that smokers tend to go gray more so than the general population, and again it's felt that it's probably due to the oxidative damage that smoke causes and how it affects the pigment-producing cells in the hair. I think eating a well-balanced diet, so you make sure that you don't develop any nutritional deficiencies, that's another thing that can be done. And modulating your stress. That's another thing you have control over, which over time can cause oxidative damage and, again, make you prone to potentially more gray hair.