- Turmeric has been widely used in traditional medicine and as a spice in foods
- Curcumin is the main active ingredient in turmeric.
- Turmeric and curcumin seem to be generally well tolerated. The most common side effects observed in clinical studies are gastrointestinal and include constipation, dyspepsia, diarrhea, distension, gastroesophageal reflux, nausea, vomiting, yellow stool and stomach ache.
- Due to their ability to increase bile secretion, turmeric and curcumin should not be taken by individuals with obstruction of the bile duct, cholangitis, liver disease, gallstones and any other biliary disease.
- Turmeric has also been linked to interactions with some conventional medicines due to its influence on some cytochrome P450 enzymes, P-glycoprotein and OATP transporters.
- Patient’s taking medicines with a narrow therapeutic index or, associated with significant side effects, e.g. anticancer or immunosuppressant agents should use turmeric and curcumin with caution.
- The quality and safety of products sold as food supplements or unlicensed products may not be guaranteed. Consumers should purchase their product from a trusted source to reduce the associated risks.
Turmeric increases bile secretion and then can cause diarrhea in some very sensitive person. - Hope that may help!
Turmeric has recently been hailed as a superfood, but did you know that it can have some serious side effects?
This, of course, applies to taking large amounts of turmeric as a supplement, not cooking the occasional dish with it – that’s generally considered perfectly safe (and tasty!)
Let’s have a look at the possible side effects turmeric can have:
READ MORE
12 surprising side effects of coconut oil
1. Risk of Excessive Bleeding
Turmeric has been found to slow down blood clotting, and this can increase the risk of bruising and bleeding in those who have bleeding disorders.
Turmeric could also interact with certain medications to cause excessive bleeding, so if you are on any medications for bleeding disorders or have bleeding disorders, stop taking turmeric.
2. Gastrointestinal Problems
Having turmeric cooked in curry hasn’t been linked to stomach issues, but high doses of turmeric over an extended period of time has been found to cause gastrointestinal problems.
Adults who consume more than the recommended amount of turmeric supplement (400 mg to 3 grams) can suffer from stomach problems – make sure you only take the recommended amount. Turmeric may also cause heartburn and indigestion.
3. Increased Risk of Gallstones and Gallbladder Issues
Turmeric contains a significant amount of oxalate, a substance that can increase the risk of developing gallstones. According to a study in the American Journal of Clinical Nutrition, urine showed increased levels of oxalate when the subjects had taken turmeric, compared to the control group.
Increased gallbladder contractions were also reported when turmeric supplements of 20-40 mg were taken. If you have gallbladder issues, it’s best to avoid turmeric supplements.
4. Lowers Blood Pressure
Blood pressure that is too low can be dangerous, and high doses of turmeric can lower blood pressure. If you take medications to lower your blood pressure, you need to be careful while taking turmeric.
5. Increased Risk of Kidney Stones
1 CUP OF TURMERIC MILK AT BEDTIME AND SEE WHAT HAPPENS TO YOUR BRAIN & BODY - Dr Mandell
As with gallstones, too much turmeric can increase the risk of developing kidney stones because of the oxalates in it. These oxalates can bind to calcium to form calcium oxalate, which is insoluble, and mainly responsible for kidney stones.
In one study, consuming turmeric led to a higher urinary oxalate excretion compared to cinnamon, so it’s wise to avoid turmeric if you have kidney problems.
6. Pregnant and Breastfeeding Women
Turmeric is safe for pregnant women to eat as a spice in food, but turmeric supplements should be avoided during pregnancy.
There is not much research available at the moment on the possible effects of turmeric on pregnant and breastfeeding women, and it’s not known if the active compounds will pass through breast milk.
7. Nausea and Diarrhea
Nausea and diarrhea are two symptoms associated with turmeric supplements, and this is because the curcumin in turmeric can cause irritation in the gastrointestinal tract.
Even low doses can cause nausea in some people, so if you notice any symptoms after taking turmeric, stop using it.
8. Don’t Use with Blood Thinning Medication
The curcumin in turmeric has been shown to reduce blood platelet function, and should be avoided by those taking blood thinning medication such as Warfarin or Coumadin.
9. May Cause Allergic Reactions
Curcumin can cause contact allergy, and some people have reported contact dermatitis and urticaria (hives) due to skin contact with turmeric. As turmeric is part of the same family as ginger, you are more likely to have a reaction if you’re allergic to ginger. If you are allergic to yellow food coloring, you may also be allergic to turmeric.
10. Could be a Factor in Infertility
If men take large amounts of turmeric supplements, it could have an effect on their testosterone levels and decrease sperm movement, which could lead to infertility.
11. May Cause Iron Deficiency
Studies have shown that some compounds in turmeric bind to iron. This could lead to a decrease in the body’s ability to absorb iron from food, which could lead to iron deficiency.
12. Avoid if You Are Having Surgery
If you are due to have an operation, avoid turmeric for one to two weeks before surgery. This is because of turmeric’s tendency to inhibit blood clotting.
Interactions with Herbs and Medicines
Turmeric might interact with the following herbs:
Turmeric Golden Milk Recipe
Black pepper Ginger
And these medications:
Blood-thinning medication like warfarin, clopidogrel, aspirin etc. Indigestion remedies such as cimetidine, famotidine, ranitidine, esomeprazole, omeprazole, and lansoprazole Diabetes medications
continua su: https://www.cookist.com/12-serious-side-effects-of-turmeric/
https://www.cookist.com/
Why does turmeric upset my stomach?
Turmeric, sometimes called Indian saffron or the golden spice, is a tall plant that grows in Asia and Central America.
The turmeric that we see on shelves and in spice cabinets is made of the ground roots of the plant. The bright yellow color of processed turmeric has inspired many cultures to use it as a dye. Ground turmeric is also a major ingredient in curry powder. Capsules, teas, powders, and extracts are some of the turmeric products available commercially.
Curcumin is the active ingredient in turmeric, and it has powerful biological properties. Ayurvedic medicine, a traditional Indian system of treatment, recommends turmeric for a variety of health conditions. These include chronic pain and inflammation. Western medicine has begun to study turmeric as a pain reliever and healing agent.
Keep reading to find out more about how turmeric might benefit your health, as well as some of its negative side effects.
Positive side effects of turmeric
It’s anti-inflammatory
The Arthritis Foundation cites several studies in which turmeric has reduced inflammation.
This anti-inflammatory ability might reduce the aggravation that people with arthritis feel in their joints.
The foundation suggests taking capsules of 400 to 600 milligrams (mg) of turmeric up to three times per day for inflammation relief.
It can relieve pain
Many people, including doctors, cite their own anecdotal experience with turmeric as a pain reliever. The spice is reputed to relieve arthritis pain as well.
Studies seem to support turmeric for pain relief, with oneTrusted Source noting that it seemed to work as well as ibuprofen (Advil) in people with arthritis in their knees. Though dosing recommendations seem to vary, those who participated in the study took 800 mgTrusted Source of turmeric in capsule form each day.
Relief Report 028: Can Turmeric Help Ease Digestive Symptoms?
It improves liver function
Turmeric has been getting attention recently because of its antioxidant abilities. The antioxidant effect of turmeric appears to be so powerful that it may stopTrusted Source your liver from being damaged by toxins. This could be good news for people who take strong drugs for diabetes or other health conditions that might hurt their liver with long-term use.
It may help reduce the risk of cancer
Curcumin shows promise as a cancer treatment. StudiesTrusted Source suggest it has protective effects against pancreatic cancer, prostate cancer, and multiple myeloma.
It can aid your digestion
Part of the reason that turmeric is in curry powder is because it adds an element of deliciousness to food. But turmeric can also play an important role in digesting that food. Because of its antioxidant and anti-inflammatory properties, turmeric can contribute to healthy digestion.
It’s used in ayurvedic medicine as a digestive healing agent. Now Western medicine has begun to studyTrusted Source how turmeric can help with gut inflammation and gut permeability, two measures of your digestive efficiency. Turmeric is even being exploredTrusted Source as a treatment for irritable bowel syndrome.
Negative side effects of turmeric
It can upset your stomach
The same agents in turmeric that support digestive health can cause irritation when taken in large amounts. Some participants in studies looking at the use of turmeric for cancer treatment had to drop outTrusted Source because their digestion was so negatively affected. Turmeric stimulates the stomach to produce more gastric acid. While this helps some people’s digestion, it can really do a number on others.
It thins your blood
Turmeric’s purifying properties may also make you bleed more easily. It’s not clear why this happens. Other suggested benefits of turmeric, such as lowered cholesterol and lowered blood pressure, probably have something to do with the way turmeric functions in your blood.
People who take blood-thinning drugs like warfarin (Coumadin) should avoidTrusted Source consuming large doses of turmeric.
It may stimulate contractions
You may have heard that eating foods seasoned with curry can stimulate labor. Although there’s little clinical data to back up this claim, studiesTrusted Source suggest turmeric can ease symptoms of PMS. So there may be something to the old wives’ tale.
Because of its blood-thinning effects alone, pregnant women should avoid taking turmeric supplements. Adding small amounts of turmeric as a spice to food shouldn’t be a problem.
The takeaway
It appears that there are health benefits to including turmeric in your diet. The golden spice supports immune health, helps relieve pain, and can aid in digestion, among other things. But because of some of its side effects, turmeric may not be worth taking for some people.
It’s important to use caution when deciding whether turmeric is something you need to try. As with any alternative therapy, speak with your doctor before you use turmeric to treat any health condition that you have.
If you want to buy a turmeric or curcumin supplement, then there is an excellent selection online with thousands of great customer reviews.
Can taking too much turmeric cause diarrhea?
Turmeric is a spice that comes from the turmeric plant. It is commonly used in Asian food. You probably know turmeric as the main spice in curry. It has a warm, bitter taste and is frequently used to flavor or color curry powders, mustards, butters, and cheeses. But the root of turmeric is also used widely to make medicine. It contains a yellow-colored chemical called curcumin, which is often used to color foods and cosmetics.
Turmeric is used for arthritis, heartburn (dyspepsia), joint pain, stomach pain, Crohn's disease and ulcerative colitis, bypass surgery, hemorrhage, diarrhea, intestinal gas, stomach bloating, loss of appetite, jaundice, liver problems, Helicobacter pylori (H. pylori) infection, stomach ulcers, irritable bowel syndrome (IBS), gallbladder disorders, high cholesterol, a skin condition called lichen planus, skin inflammation from radiation treatment, and fatigue.
It is also used for headaches, bronchitis, colds, lung infections, fibromyalgia, leprosy, fever, menstrual problems, itchy skin, recovery after surgery, and cancers. Other uses include depression, Alzheimer's disease, swelling in the middle layer of the eye (anterior uveitis), diabetes, water retention, worms, an autoimmune disease called systemic lupus erythematosus (SLE), tuberculosis, urinary bladder inflammation, and kidney problems.
Some people apply turmeric to the skin for pain, ringworm, sprains and swellings, bruising, leech bites, eye infections, acne, inflammatory skin conditions and skin sores, soreness inside of the mouth, infected wounds, and gum disease.
Turmeric is also used as an enema for people with inflammatory bowel disease.
In food and manufacturing, the essential oil of turmeric is used in perfumes, and its resin is used as a flavor and color component in foods.
Don't confuse turmeric with Javanese turmeric root (Curcuma zedoaria).
How does it work?
Turmeric contains the chemical curcumin. Curcumin and other chemicals in turmeric might decrease swelling (inflammation). Because of this, turmeric might be beneficial for treating conditions that involve inflammation.
SLIDESHOW
Digestive Disorders: Common Misconceptions
See Slideshow
Inflammatory Bowel Disease Causes, Symptoms and Treatment | San Diego Health
USES & EFFECTIVENESS
Possibly Effective for...
High cholesterol. Research suggests that taking turmeric extract by mouth twice daily for 3 months reduces total cholesterol, low-density lipoprotein (LDL or "bad") cholesterol, and triglycerides in overweight people with high cholesterol.
Osteoarthritis. Some research shows that taking turmeric extracts, alone or in combination with other herbal ingredients, can reduce pain and improve function in people with osteoarthritis. In some research, turmeric worked about as well as ibuprofen for reducing osteoarthritis pain. However, it does not seem to work as well as diclofenac for improving pain and function in people with osteoarthritis.
Itching (pruritus). Research suggests that taking turmeric by mouth three times daily for 8 weeks reduces itching in people with long-term kidney disease. Also, early research suggests that taking a specific combination product (C3 Complex, Sami Labs LTD) containing curcumin plus black pepper or long pepper daily for 4 weeks reduces itching severity and improves quality of life in people with chronic itching caused by mustard gas.
Possibly Ineffective for...
Stomach ulcers. Some research suggests that taking turmeric three times daily for 8 weeks does not improve stomach ulcers. Also, taking powdered turmeric four times daily for 6 weeks seems to be less effective than taking a conventional antacid.
Insufficient Evidence to Rate Effectiveness for...
Alzheimer's disease. Early research shows that taking curcumin, a chemical found in turmeric, daily for 6 months does not benefit people with Alzheimer's disease.
Eye inflammation (anterior uveitis). Early research suggests that taking curcumin, a chemical found in turmeric, might improve symptoms of long-term inflammation in the middle layer of the eye.
Colorectal cancer. Early research suggests that taking a specific turmeric product containing turmeric extract and Javanese turmeric extract (P54FP, Phytopharm plc., Godmanchester, United Kingdom) might stabilize some measures of colon cancer. There is also early evidence that taking curcumin, a chemical found in turmeric, daily for 30 days can reduce the number of precancerous glands in the colon of people at high risk of cancer.
Bypass surgery (coronary artery bypass graft surgery). Early research suggests that taking curcuminoids, which are chemicals found in turmeric, starting 3 days before surgery and continuing for 5 days after surgery can lower the risk of a heart attack following bypass surgery.
Skin wounds related to cancer. Early research suggests that applying a turmeric ointment might help to relieve odor and itching caused by wounds associated with different types of cancer.
A type of inflammatory bowel disease called Crohn's disease. Some evidence suggests that taking curcumin, a chemical found in turmeric, daily for one month can reduce bowel movements, diarrhea, and stomach pain in people with Crohn's disease.
Depression. Early research suggests that taking curcumin, a chemical found in turmeric, twice daily for 6 weeks is as effective as the antidepressant medication fluoxetine in people with depression.
Diabetes. Early research suggests that taking turmeric extract twice daily for 9 months can reduce the number of people with prediabetes who develop diabetes.
Stomach upset (dyspepsia). Some research shows that taking turmeric by mouth four times daily for 7 days might help improve an upset stomach.
Gum disease (gingivitis). Early research suggests that using a turmeric mouthwash is as effective as a drug-therapy mouthwash for reducing gum disease and bacteria levels in the mouth of people with gingivitis.
Stomach ulcers caused by Helicobacter pylori (H pylori) infection. Early research suggests that taking turmeric daily for 4 weeks is less effective than conventional treatment for eliminating certain bacteria (H. pylori) that can cause stomach ulcers.
Irritable bowel syndrome (IBS). Early research suggests that taking a turmeric extract (Cynara Turmeric, Lchtwer Pharma) daily for 8 weeks reduces the occurrence of IBS in people with IBS who are otherwise healthy.
Joint pain. Research shows that taking a specific combination product (Instaflex Joint Support, Direct Digital, Charlotte, NC) containing turmeric and other ingredients three times daily for 8 weeks reduces the severity of joint pain. But it does not appear to help joint stiffness or improve joint function.
Skin rash (Lichen planus). Taking a certain product (Curcumin C3 Complex, Sabinsa Corp) containing chemicals found in turmeric three times daily for 12 days can reduce skin irritation caused by lichen planus.
Prostate cancer. Research suggests that taking a formula containing broccoli powder, turmeric powder, pomegranate whole fruit powder, and green tea extract three times daily for 6 months prevents an increase in prostate specific antigen (PSA) levels in men with prostate cancer. PSA levels are measured to monitor how well prostate cancer treatment is working. However, it's not yet known if this formula reduces the risk of prostate cancer progression or recurrence.
Inflammation in the mouth and/or esophagus from radiation treatment. Early research suggests that swishing a turmeric solution in the mouth six times daily for 6 weeks reduces the risk of inflammation in the mouth and/or esophagus caused by radiation treatment in people with head and neck cancer.
Rheumatoid arthritis (RA). Early research suggests that curcumin, a chemical found in turmeric, might reduce some RA symptoms, including morning stiffness, walking time, and joint swelling. Other research shows that taking a turmeric product (BCM-95, Arjuna Natural Extracts, India) twice daily reduces RA symptoms more than conventional medication.
Recover from surgery. Early research suggests that taking curcumin, a chemical found in turmeric, daily for up to one week after surgery can reduce pain, fatigue, and the need for pain medications.
An inflammatory disease called systemic lupus erythematosus (SLE). Early research suggests that taking turmeric by mouth three times daily for 3 months can reduce blood pressure and improve kidney function in people with kidney inflammation (lupus nephritis) caused by systemic lupus erythematosus.
Tuberculosis. Early research suggests that taking a product containing turmeric and Tinospora cordifolia can reduce bacteria levels, improve wound healing, and reduce liver toxicity caused by antituberculosis therapy in people with tuberculosis who are receiving antituberculosis therapy.
A type of inflammatory bowel disease called ulcerative colitis. Some early research suggests that taking curcumin, a chemical found in turmeric, daily for up to 6 months can reduce symptoms and the recurrence of ulcerative colitis when used in combination with conventional treatments. Other research shows that taking turmeric extract as an enema might help people with this condition.
Acne.
Jaundice.
Hepatitis.
Diarrhea.
Fibromyalgia.
Liver and gallbladder problems.
Headache.
Menstrual problems.
Pain.
Ringworm.
Bruising.
Other conditions.
More evidence is needed to rate turmeric for these uses.
Natural Medicines Comprehensive Database rates effectiveness based on scientific evidence according to the following scale: Effective, Likely Effective, Possibly Effective, Possibly Ineffective, Likely Ineffective, and Insufficient Evidence to Rate (detailed description of each of the ratings).
Managing your IBS-D
SIDE EFFECTS
Turmeric is LIKELY SAFE when taken by mouth or applied to the skin appropriately for up to 8 months.
Turmeric is POSSIBLY SAFE when it is used as an enema or a mouthwash in the short-term.
Turmeric usually does not cause significant side effects; however, some people can experience stomach upset, nausea, dizziness, or diarrhea.
In one report, a person who took very high amounts of turmeric, over 1500 mg twice daily, experienced a dangerous abnormal heart rhythm. However, it is unclear if turmeric was the actual cause of this side effect. Until more is known, avoid taking excessively large doses of turmeric.
SPECIAL PRECAUTIONS & WARNINGS
Pregnancy and breast-feeding: During pregnancy and while breast-feeding, turmeric is LIKELY SAFE when taken by mouth in amounts commonly found in food. However, turmeric is LIKELY UNSAFE when taken by mouth in medicinal amounts during pregnancy. It might promote a menstrual period or stimulate the uterus, putting the pregnancy at risk. Do not take medicinal amounts of turmeric if you are pregnant. There is not enough information to rate the safety of medicinal amounts of turmeric during breast-feeding. It is best not to use it.
Gallbladder problems: Turmeric can make gallbladder problems worse. Do not use turmeric if you have gallstones or a bile duct obstruction.
Bleeding problems: Taking turmeric might slow blood clotting. This might increase the risk of bruising and bleeding in people with bleeding disorders.
Diabetes: Curcumin, a chemical in turmeric, might decrease blood sugar in people with diabetes. Use with caution in people with diabetes as it might make blood sugar too low.
A stomach disorder called gastroesophageal reflux disease (GERD): Turmeric can cause stomach upset in some people. It might make stomach problems such as GERD worse. Do not take turmeric if it worsens symptoms of GERD.
Hormone-sensitive condition such as breast cancer, uterine cancer, ovarian cancer, endometriosis, or uterine fibroids: Turmeric contains a chemical called curcumin, which might act like the hormone estrogen. In theory, turmeric might make hormone-sensitive conditions worse. However, some research shows that turmeric reduces the effects of estrogen in some hormone-sensitive cancer cells. Therefore, turmeric might have beneficial effects on hormone-sensitive conditions. Until more is known, use cautiously if you have a condition that might be made worse by exposure to hormones.
Infertility: Turmeric might lower testosterone levels and decrease sperm movement when taken by mouth by men. This might reduce fertility. Turmeric should be used cautiously by people trying to have a baby.
Iron deficiency: Taking high amounts of turmeric might prevent the absorption of iron. Turmeric should be used with caution in people with iron deficiency.
Surgery: Turmeric might slow blood clotting. It might cause extra bleeding during and after surgery. Stop using turmeric at least 2 weeks before a scheduled surgery.
INTERACTIONS
Medications changed by the liver (Cytochrome P450 3A4 (CYP3A4) substrates)Interaction Rating: Moderate Be cautious with this combination.Talk with your health provider.
Some medications are changed and broken down by the liver. Turmeric might decrease how quickly the liver breaks down some medications. Taking turmeric along with some medications that are broken down by the liver can increase the effects and side effects of some medications. Before taking turmeric talk to your healthcare provider if you take any medications that are changed by the liver.
Some medications that are changed by the liver include some calcium channel blockers (diltiazem, nicardipine, verapamil), chemotherapeutic agents (etoposide, paclitaxel, vinblastine, vincristine, vindesine), antifungals (ketoconazole, itraconazole), glucocorticoids, alfentanil (Alfenta), cisapride (Propulsid), fentanyl (Sublimaze), lidocaine (Xylocaine), losartan (Cozaar), fexofenadine (Allegra), midazolam (Versed), and others.
Medications for diabetes (Antidiabetes drugs)Interaction Rating: Moderate Be cautious with this combination.Talk with your health provider.
Turmeric might decrease blood sugar in people with type 2 diabetes. Diabetes medications are also used to lower blood sugar. Taking turmeric along with diabetes medications might cause your blood sugar to go too low. Monitor your blood sugar closely. The dose of your diabetes medication might need to be changed.
5 ways to stop diarrhea || Diarrhea Treatment Fast || Sameer Islam Videos
Some medications used for diabetes include glimepiride (Amaryl), glyburide (DiaBeta, Glynase PresTab, Micronase), insulin, pioglitazone (Actos), rosiglitazone (Avandia), chlorpropamide (Diabinese), glipizide (Glucotrol), tolbutamide (Orinase), and others.
Medications that slow blood clotting (Anticoagulant / Antiplatelet drugs)Interaction Rating: Moderate Be cautious with this combination.Talk with your health provider.
Turmeric might slow blood clotting. Taking turmeric along with medications that also slow clotting might increase the chances of bruising and bleeding.
Some medications that slow blood clotting include aspirin, clopidogrel (Plavix), diclofenac (Voltaren, Cataflam, others), ibuprofen (Advil, Motrin, others), naproxen (Anaprox, Naprosyn, others), dalteparin (Fragmin), enoxaparin (Lovenox), heparin, warfarin (Coumadin), and others.
Sulfasalazine (Azulfidine EN-Tabs)Interaction Rating: Moderate Be cautious with this combination.Talk with your health provider.
Turmeric might increase how much sulfasalazine (Azulfidine EN-Tabs) the body absorbs. Taking turmeric while taking sulfasalazine (Azulfidine EN-Tabs) might increase the effects and side effects of sulfasalazine (Azulfidine EN-Tabs).
Tacrolimus (Prograf)Interaction Rating: Moderate Be cautious with this combination.Talk with your health provider.
Turmeric might increase the amount of tacrolimus in the body. This can increase the side effects of tacrolimus and even damage the kidneys.
TalinololInteraction Rating: Moderate Be cautious with this combination.Talk with your health provider.
Turmeric might decrease how much talinolol the body absorbs. Taking turmeric while taking talinolol might decrease the effects and side effects of talinolol.
Docetaxel (Docefrez, Taxotere)Interaction Rating: Minor Be cautious with this combination.Talk with your health provider.
Turmeric might increase how much docetaxel (Docefrex, Taxotere) the body absorbs. Taking turmeric while taking docetaxel (Docefrex, Taxotere) might increase the effects and side effects of docetaxel (Docefrex, Taxotere).
EstrogensInteraction Rating: Minor Be cautious with this combination.Talk with your health provider.
Large amounts of turmeric might have some of the same effects as estrogen. However, large amounts of turmeric are not as strong as estrogen pills. Taking turmeric along with estrogen pills might decrease the effects of estrogen pills.
Some estrogen pills include conjugated equine estrogens (Premarin), ethinyl estradiol, estradiol, and others.
Medications changed by the liver (Cytochrome P450 1A1 (CYP1A1) substrates)Interaction Rating: Minor Be cautious with this combination.Talk with your health provider.
Some medications are changed and broken down by the liver. Turmeric might decrease how quickly the liver breaks down some medications. Taking turmeric along with some medications that are broken down by the liver can increase the effects and side effects of some medications. Before taking turmeric talk to your healthcare provider if you take any medications that are changed by the liver.
Some medications that are changed by the liver include chlorzoxazone (Lorzone), theophylline, and bufuralol.
Medications changed by the liver (Cytochrome P450 1A2 (CYP1A2) substrates)Interaction Rating: Minor Be cautious with this combination.Talk with your health provider.
Some medications are changed and broken down by the liver. Turmeric might decrease how quickly the liver breaks down some medications. Taking turmeric along with some medications that are broken down by the liver can increase the effects and side effects of some medications. Before taking turmeric talk to your healthcare provider if you take any medications that are changed by the liver.
Some medications that are changed by the liver include clozapine (Clozaril), cyclobenzaprine (Flexeril), fluvoxamine (Luvox), haloperidol (Haldol), imipramine (Tofranil), mexiletine (Mexitil), olanzapine (Zyprexa), pentazocine (Talwin), propranolol (Inderal), tacrine (Cognex), zileuton (Zyflo), zolmitriptan (Zomig), and others.
Chronic Diarrhea: Approach to Cause, Secretory vs Osmotic vs Inflammatory, Watery vs Bloody Diarrhea
Medications moved by pumps in cells (P-Glycoprotein Substrates)Interaction Rating: Minor Be cautious with this combination.Talk with your health provider.
Some medications are moved by pumps in cells. Turmeric might make these pumps less active and increase how much of some medications get absorbed by the body. This might increase the amount of some medications in the body, which could lead to more side effects. But there is not enough information to know if this is a big concern.
Some medications that are moved by these pumps include some chemotherapeutic agents (etoposide, paclitaxel, vinblastine, vincristine, vindesine), antifungals (ketoconazole, itraconazole), protease inhibitors (amprenavir, indinavir, nelfinavir, saquinavir), H2 antagonists (cimetidine, ranitidine), some calcium channel blockers (diltiazem, verapamil), digoxin, corticosteroids, erythromycin, cisapride (Propulsid), fexofenadine (Allegra), cyclosporine, loperamide (Imodium), quinidine, and others.
Norfloxacin (Noroxin)Interaction Rating: Minor Be cautious with this combination.Talk with your health provider.
Turmeric might increase how much norfloxacin (Noroxin) the body absorbs. Taking turmeric while taking norfloxacin (Noroxin) might increase the effects and side effects of norfloxacin (Noroxin).
Paclitaxel (Abraxane, Onxol)Interaction Rating: Minor Be cautious with this combination.Talk with your health provider.
Turmeric might increase how much paclitaxel (Abraxane, Onxol) the body absorbs. Taking turmeric while taking paclitaxel (Abraxane, Onxol) might increase the effects and side effects of paclitaxel (Abraxane, Onxol). However, there is not enough information to know if this is a big concern.
DOSING
ADULTS
BY MOUTH:
For high cholesterol: 1.4 grams of turmeric extract in two divided doses daily for 3 months has been used.
For itching (pruritus): 1500 mg of turmeric in three divided doses daily for 8 weeks has been used. Also, a specific product containing turmeric extract (C3 Complex, Sami Labs LTD) plus black pepper or long pepper has been used daily for 4 weeks.
For osteoarthritis: 500 mg of a non-commercial turmeric product four times daily for 4-6 weeks has been used. 500 mg of a specific turmeric extract (Turmacin, Natural Remedies Pvt. Ltd.) has been used twice daily for 6 weeks (89721). 500 mg of a specific turmeric extract (Meriva, Indena) containing turmeric and phosphatidylcholine has been used twice daily for 2-3 months. Other combination products have also been used.
CHILDREN
BY MOUTH:
For high cholesterol: 1.4 grams of turmeric extract in two divided doses daily for 3 months has been used in children at least 15 years-old.
Turmeric has most often been used by adults in doses of up to 1.5 grams daily for up to 9 months. It is also sometimes used in mouthwashes, gels, creams, and tonics. Speak with a healthcare provider to find out what dose might be best for a specific condition.
Turmeric is a common spice that comes from the root of Curcuma longa. It contains a chemical called curcumin, which might reduce swelling.
Turmeric has a warm, bitter taste and is frequently used to flavor or color curry powders, mustards, butters, and cheeses. Because curcumin and other chemicals in turmeric might decrease swelling, it is often used to treat conditions that involve pain and inflammation.
What Are the Causes of Chronic Diarrhea
People commonly use turmeric for osteoarthritis. It is also used for hay fever, depression, high cholesterol, a type of liver disease, and itching, but there is no good scientific evidence to support most of these uses. There is also no good evidence to support using turmeric for COVID-19.
Don't confuse turmeric with Javanese turmeric root or tree turmeric. Also, don't confuse it with zedoary or goldenseal, which are unrelated plants that are sometimes called turmeric.
Possibly Effective for
Hay fever. Taking turmeric by mouth seems to reduce hay fever symptoms such as sneezing, itching, runny nose, and congestion.
Depression. Most research shows that taking curcumin, a chemical found in turmeric, by mouth reduces depression symptoms in people already using an antidepressant.
High levels of cholesterol or other fats (lipids) in the blood (hyperlipidemia). Taking turmeric by mouth seems to lower levels of blood fats called triglycerides. But the effects of turmeric on cholesterol levels are conflicting. Also, there are many different turmeric products available. It is not known which ones work best.
Buildup of fat in the liver in people who drink little or no alcohol (nonalcoholic fatty liver disease or NAFLD). Taking turmeric extract by mouth reduces markers of liver injury in people who have this condition. It also seems to help prevent the build-up of more fat in the liver.
Swelling (inflammation) and sores inside the mouth (oral mucositis). Taking curcumin, a chemical found in turmeric, by mouth, or as a lozenge or mouthwash, seems to prevent swelling and sores in the mouth during radiation treatment for cancer.
Osteoarthritis. Taking turmeric extracts, alone or together with other herbal ingredients, can reduce pain and improve function in people with knee osteoarthritis. Turmeric might work about as well as ibuprofen for reducing pain. But it doesn't seem to work as well as another drug, called diclofenac.
Itching. Taking turmeric by mouth might reduce itching that is caused by various conditions.
Possibly Ineffective for
Alzheimer disease. Taking turmeric, or a chemical in turmeric called curcumin, by mouth does not seem to improve symptoms of Alzheimer disease.
Stomach ulcers. Taking turmeric by mouth does not seem to improve stomach ulcers.
There is interest in using turmeric for a number of other purposes, but there isn't enough reliable information to say whether it might be helpful.
When taken by mouth: Turmeric is likely safe when used short-term. Turmeric products that provide up to 8 grams of curcumin daily seem to be safe when used for up to 2 months, Also, taking up to 3 grams of turmeric daily seems to be safe when used for up to 3 months. Turmeric usually doesn't cause serious side effects. Some people can experience mild side effects such as stomach upset, nausea, dizziness, or diarrhea. These side effects are more common at higher doses.
When applied to the skin: Turmeric is likely safe. It is possibly safe when turmeric is applied inside the mouth as a mouthwash.
When applied into the rectum: Turmeric is possibly safe when used as an enema.
Pregnancy: Turmeric is commonly used in small amounts as a spice in foods. But it's likely unsafe to use larger amounts of turmeric as a medicine during pregnancy. It might cause a menstrual period or stimulate the uterus, putting the pregnancy at risk. Do not take medicinal amounts of turmeric if you are pregnant.
Breast-feeding: Turmeric is commonly used in small amounts as a spice in foods. But there isn't enough reliable information to know if turmeric is safe to use in medicinal amounts during breast-feeding. Stay on the safe side and avoid use.
Side Effects of Turmeric Tea
Gallbladder problems: Turmeric can make gallbladder problems worse. Do not use turmeric if you have gallstones or a bile duct obstruction.
Moderate Interaction
Be cautious with this combination
Medications that slow blood clotting (Anticoagulant / Antiplatelet drugs) interacts with TURMERIC
Turmeric might slow blood clotting. Taking turmeric along with medications that also slow blood clotting might increase the risk of bruising and bleeding.
Medications for diabetes (Antidiabetes drugs) interacts with TURMERIC
Turmeric might lower blood sugar levels. Taking turmeric along with diabetes medications might cause blood sugar to drop too low. Monitor your blood sugar closely.
Talinolol interacts with TURMERIC
Turmeric might decrease how much Talinolol the body absorbs. Taking turmeric while taking Talinolol might decrease the effects and side effects of Talinolol.
Sulfasalazine (Azulfidine) interacts with TURMERIC
Turmeric might increase how much sulfasalazine the body absorbs. Taking turmeric while taking sulfasalazine might increase the effects and side effects of sulfasalazine.
Tacrolimus (Prograf) interacts with TURMERIC
Warfarin (Coumadin) interacts with TURMERIC
Warfarin is used to slow blood clotting. Taking turmeric while taking warfarin might increase the effects of warfarin and increase the risk of bleeding and bruising.
Medications for cancer (Alkylating agents) interacts with TURMERIC
Turmeric is an antioxidant. There is some concern that antioxidants might decrease the effects of some medications used for cancer. If you are taking medications for cancer, check with your healthcare provider before taking turmeric.
Medications for cancer (Antitumor antibiotics) interacts with TURMERIC
Turmeric is an antioxidant. There is some concern that antioxidants might decrease the effects of medications used for cancer. If you are taking medications for cancer, check with your healthcare provider before taking turmeric.
Medications for cancer (Topoisomerase I inhibitors) interacts with TURMERIC
Turmeric is an antioxidant. There is some concern that antioxidants might decrease the effectiveness of some medications used for cancers. If you are taking medications for cancer, check with your healthcare provider before taking turmeric.
Amlodipine (Norvasc) interacts with TURMERIC
Turmeric might increase how much amlodipine the body absorbs. Taking turmeric while taking amlodipine might increase the effects and side effects of amlodipine.
Medications that can harm the liver (Hepatotoxic drugs) interacts with TURMERIC
Turmeric might harm the liver. Some medications can also harm the liver. Taking turmeric along with a medication that can harm the liver might increase the risk of liver damage.
5 Simple Steps to Cure IBS without Drugs
Minor Interaction
Be watchful with this combination
Medications changed by the liver (Cytochrome P450 1A1 (CYP1A1) substrates) interacts with TURMERIC
Some medications are changed and broken down by the liver. Turmeric might change how quickly the liver breaks down these medications. This could change the effects and side effects of these medications.
Medications changed by the liver (Cytochrome P450 1A2 (CYP1A2) substrates) interacts with TURMERIC
Some medications are changed and broken down by the liver. Turmeric might change how quickly the liver breaks down these medications. This could change the effects and side effects of these medications.
Medications changed by the liver (Cytochrome P450 3A4 (CYP3A4) substrates) interacts with TURMERIC
Some medications are changed and broken down by the liver. Turmeric might change how quickly the liver breaks down these medications. This could change the effects and side effects of these medications.
Estrogens interacts with TURMERIC
Large amounts of turmeric might interfere with the effects of estrogen. Taking turmeric along with estrogen might decrease the effects of estrogens.
Some estrogen pills include conjugated equine estrogens (Premarin), ethinyl estradiol, estradiol, and others.
Norfloxacin (Noroxin) interacts with TURMERIC
Turmeric might increase how much norfloxacin the body absorbs. Taking turmeric while taking norfloxacin might increase the effects and side effects of norfloxacin.
Medications moved by pumps in cells (P-Glycoprotein Substrates) interacts with TURMERIC
Some medications are moved in and out of cells by pumps. Turmeric might change how these pumps work and change how much medication stays in the body. In some cases, this might change the effects and side effects of a medication.
Irritable bowel syndrome: Mayo Clinic Radio
Paclitaxel (Abraxane, Onxol) interacts with TURMERIC
Turmeric might increase how much paclitaxel the body absorbs. Taking turmeric while taking paclitaxel might increase the effects and side effects of paclitaxel. However, there is not enough information to know if this is a big concern.
Docetaxel (Taxotere) interacts with TURMERIC
Turmeric might increase how much docetaxel the body absorbs. Taking turmeric while taking docetaxel might increase the effects and side effects of docetaxel.
Glyburide (Diabeta, others) interacts with TURMERIC
Turmeric contains curcumin. Curcumin might lower blood sugar. Glyburide is also used to lower blood sugar. Taking curcumin or turmeric along with glyburide might cause your blood sugar to go too low. Monitor your blood sugar closely. Your dose of glyburide might need to be changed.
Bleeding problems: Taking turmeric might slow blood clotting. This might increase the risk of bruising and bleeding in people with bleeding disorders.
Cure Diarrhea Fast (HUMANS & DOGS)- Grandma's Natural Home Remedy
Hormone-sensitive condition such as breast cancer, uterine cancer, ovarian cancer, endometriosis, or uterine fibroids: Turmeric contains a chemical called curcumin, which might act like the hormone estrogen. In theory, this might have effects on hormone-sensitive conditions. Until more is known, use cautiously if you have a condition that might be made worse by exposure to hormones.
Infertility: Turmeric might lower testosterone levels and decrease sperm movement. This might reduce fertility. Turmeric should be used cautiously by people trying to have a baby.
Liver disease: There is some concern that turmeric can damage the liver, especially in people who have liver disease. Don't use turmeric if you have liver problems.
Surgery: Turmeric might slow blood clotting. It might cause extra bleeding during and after surgery. Stop using turmeric at least 2 weeks before a scheduled surgery.
No comments:
Post a Comment